The Psychiatry and Addiction World Conference 2025 in Singapore will focus on Mental Wellness, which plays a central role in psychiatric care and addiction treatment. This topic also reflects the conference's theme, "Future Directions in Psychiatry and Addiction Research." Mental wellness refers to a person's ability to deal with daily stress, work effectively, and engage in all aspects of community life. Cutting-edge research, innovative treatment approaches, and effective preventive strategies to advance mental health in clinical and community settings will be presented to leading experts during the Psychiatry and Addiction World Conference (PAWC 2025).