During this presentation, we will closely examine the notion of Responsibility and its different implications for Responsible Gambling and Drinking. An operational definition of Responsibility will be suggested and the various impacts on consumers’ and patrons’ activities. Furthermore, we will consider some of the complex value judgments and related conceptual difficulties that underpin attempts to promote Responsible Gambling. Finally, the role of responsibility for different stakeholders such as operators, regulators, consumers, etc. will be examined. The conclusion will sort out the importance of including the notion of “Responsibility” in the understanding, prevention and treatment of gambling and drinking behaviours.